
Ground Beef Zucchini Casserole is that cozy dinner you crave when the air gets chilly and everyone’s hungry. It brings together savory seasoned beef juicy bites of zucchini and plenty of melted cheese for a meal that is simple enough for weeknights and special enough to share. Even picky eaters in my house find empty plates with this satisfying casserole and I love how easy it is to make ahead or tweak to fit what is in the fridge.
The first time I made this was for a neighbor potluck and not a single scoop was left This dish quickly turned into my favorite way to use up zucchini from summer gardens.
Ingredients
- Lean ground beef: brings protein and richness Use fresh ground beef with a pink color and no gray spots
- Zucchini: provides moisture and tender bite Choose firm zucchinis with shiny skin and no soft spots
- Sweet onion: gives depth and mild sweetness Go for onion with tight skin and a fresh clean scent
- Garlic: bumps up the savory flavor and warmth Use firm cloves and avoid any sprouting
- Low sodium tomato sauce: ties everything together with tang and juiciness Canned or homemade both work nicely
- Shredded mozzarella cheese: melts into gooey goodness Freshly shredded cheese melts better than pre-bagged
- Italian seasoning: mixes herbs for classic taste Smell before using for freshness
- Olive oil: helps brown the beef and adds a silkiness Look for extra virgin olive oil with a grassy aroma
- Salt and pepper: round out and sharpen all the flavors Freshly ground black pepper makes a big difference
Step-by-Step Instructions
- Brown the Beef:
- In a large skillet add olive oil and warm over medium heat Add ground beef and cook gently breaking it up until no pink remains and beef is browned You want crumbles not big clumps which brown better for flavor
- Add Aromatics:
- Stir in finely chopped onions and minced garlic Let cook for three to five minutes until onions turn translucent and release their sweetness The gentle sauté builds a rich base for the casserole
- Simmer with Sauce and Zucchini:
- Pour in tomato sauce then add diced zucchini and Italian seasoning Season generously with salt and pepper Let everything simmer for five minutes so the zucchini starts to soften but does not get mushy This step ensures flavors mingle
- Layer in Baking Dish:
- In your baking dish spoon in half the beef and zucchini mixture Spread evenly Top with half the mozzarella cheese Repeat layers with remaining meat and cheese so every bite gets a mix of flavors
- Bake to Finish:
- Cover the baking dish tightly with foil This keeps moisture in and helps everything meld Bake at 375 degrees for twenty five minutes Uncover and bake ten to fifteen minutes longer until the top is golden with bubbling cheese

Zucchini is my family’s secret trick for moisture and nutrition in casseroles Even picky eaters love it when it is mixed with the beef and cheese My kids like to help layer the cheese and always sneak little bites before the dish goes in the oven
Storage Tips
Let the casserole cool completely before covering and storing in the fridge Individual portions stay fresh for three days and you can also freeze slices wrapped tightly for quick meals later To reheat cover lightly and bake at three hundred fifty degrees until hot or microwave single portions
Ingredient Substitutions
Ground turkey or chicken can replace beef for a lighter flavor Add red pepper flakes or a pinch of smoked paprika for extra kick If you are out of mozzarella use cheddar or Monterey Jack for a different cheesy twist Summer harvests often mean heaps of zucchini on hand but yellow squash works well too
Serving Suggestions
This casserole shines as a main dish on its own but is extra tasty with a side of garlic bread or crisp green salad A spoonful of sour cream or fresh basil sprinkled on top boosts flavor even more Any leftovers work well packed for lunch and are a hit with kids after school

Cultural and Historical Context
Casseroles became popular in American kitchens for their ease and ability to stretch ingredients during busy times This version takes the classic ground beef combo and lightens it up a bit with garden zucchini Italian flavors and bubbling cheese It brings together both comfort and a bit of nostalgia making it a new family favorite
Recipe FAQs
- → Can I use ground turkey instead of beef?
Absolutely! Ground turkey is a great substitute and will still provide a hearty base while reducing fat content.
- → Should zucchini be peeled before adding?
No need to peel zucchini—the skin adds texture and nutrients to the finished dish.
- → What other cheese can I use?
Cheddar, Monterey Jack, or a blend of Italian cheeses work well if you wish to change up the flavor profile.
- → How do I prevent a watery casserole?
Be sure to dice zucchini and sauté briefly with beef to release extra moisture before baking.
- → Can leftovers be frozen?
Yes, cool completely and store in an airtight container or freezer-safe bag for up to 2 months.
- → Is this dish gluten-free?
Yes, as written, this casserole does not contain gluten ingredients. Verify your tomato sauce for cross-contamination.